SCHEMBL1334971

SCHEMBL1334971

CCc1cc(CC)c(N)c(CS)c1N

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
DHFR P00374 1/20 0.33
TDP1 Q9NUW8 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334943 0.96 HTT (0.39) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL1334762 0.87 ALDH1A1 (0.42) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL1334752 0.86 HTT (0.39) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL117142 0.82 HTT (0.46) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL1334766 0.82 MAPT (0.33) MAPTTDP1
SCHEMBL28243768 0.82 HTT (0.39) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL1334970 0.81 POLB (0.33) HTTPOLBMAPTNOS3NOS2
SCHEMBL393744 0.78 HTT (0.43) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL1334753 0.77 HTT (0.41) HTTPOLBMAPTALDH1A1NOS3
SCHEMBL27612200 0.76 HTT (0.50) HTTPOLBMAPTALDH1A1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2351638-B1 PLASTIC LENS MANUFACTURING METHOD AND MANUFACTURING DEVICE HOYA CORP (JP) 2016-11-23 EP disclosed
EP-1759824-B1 METHOD OF MANUFACTURING PLASTIC LENSES HOYA CORP (JP) 2016-03-09 EP disclosed
US-20150259509-A1 TRANSPARENT MOLDED ARTICLE, OPTICAL MEMBER, PLASTIC LENS, AND METHODS OF MANUFACTURING SAME HOYA CORPORATION (JP) 2015-09-17 US disclosed
CN-101648421-B Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens cas HOYA CORPORATION (JP) 2014-10-15 CN disclosed
US-8377345-B2 Method of manufacturing optical member, method of manufacturing plastic lens, gasket for molding plastic lens, and jog for casting monomer HOYA CORPORATION (JP) 2013-02-19 US disclosed
US-8372317-B2 Method of casting plastic lens starting material liquid and casting apparatus and method of manufacturing plastic lens HOYA CORPORATION (JP) 2013-02-12 US disclosed
US-20110278747-A1 MANUFACTURING METHOD AND MANUFACTURING APPARATUS OF PLASTIC LENS HOYA CORPORATION (JP) 2011-11-17 US disclosed
CN-102202856-A Plastic lens manufacturing method and manufacturing device HOYA CORP 2011-09-28 CN disclosed
EP-2351638-A1 PLASTIC LENS MANUFACTURING METHOD AND MANUFACTURING DEVICE Hoya Corporation (JP) 2011-08-03 EP disclosed
US-7919020-B2 Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens casting mold, and plastic lens manufacturing apparatus HOYA CORPORATION (JP) 2011-04-05 US disclosed
US-7682531-B2 Process for producing optical member HOYA CORPORATION (JP) 2010-03-23 US disclosed
US-20100032852-A1 METHOD OF CASTING PLASTIC LENS STARTING MATERIAL LIQUID AND CASTING APPARATUS, AND METHOD OF MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2010-02-11 US disclosed
EP-2133187-A1 METHOD AND DEVICE FOR POURING PLASTIC LENS MATERIAL LIQUID AND METHOD OF PRODUCING PLASTIC LENS Hoya Corporation (JP) 2009-12-16 EP disclosed
EP-1384736-B1 TRANSPARENT MOLDED OBJECTS, OPTICAL MEMBER, PLASTIC LENS, AND PROCESSES FOR PRODUCING THESE HOYA CORP (JP) 2009-08-12 EP disclosed
US-20080029914-A1 Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens casting mold, and plastic lens manufacturing apparatus HOYA CORPORATION (JP) 2008-02-07 US disclosed
US-20080018005-A1 Method Of Manufacturing Plastic Lens, Gasket For Molding Plastic Lens, Casting Mold For Molding Plastic Lens, Casting Jig For Plastic Lens Starting Material Liquid, Holding Member For Plastic Lens Casting Mold, And Plastic Lens Manufacturing Apparatus HOYA CORPORATION 2008-01-24 US disclosed
US-20060155093-A1 Polyol compound, transparent molded article and method of manufacturing transparent molded article HOYA CORPORATION (JP) 2006-07-13 US disclosed
EP-1640394-A1 POLYOL COMPOUND, TRANSPARENT MOLDED OBJECTS, AND PROCESS FOR PRODUCING TRANSPARENT MOLDED OBJECT HOYA CORPORATION (JP) 2006-03-29 EP disclosed
US-20050200033-A1 Process for producing optical member, process for producing plastic lens, gasket for plastic lens molding, and jig for monomer injection HOYA CORPORATION (JP) 2005-09-15 US disclosed
EP-1504869-A1 PROCESS FOR PRODUCING OPTICAL MEMBER, PROCESS FOR PRODUCING PLASTIC LENS, GASKET FOR PLASTIC LENS MOLDING, AND JIG FOR MONOMER INJECTION HOYA CORPORATION (JP) 2005-02-09 EP disclosed