Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.48 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.48 |
| ▸ | GLI1 | P08151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526193 | 1.00 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL14398790 | 0.92 | GPBAR1 (0.64) | GPBAR1LMNANT5ESMN1; SMN2GLI1 | |
| SCHEMBL13351911 | 0.92 | GPBAR1 (0.64) | GPBAR1LMNANT5ESMN1; SMN2GLI1 | |
| SCHEMBL3525117 | 0.92 | GPBAR1 (0.64) | GPBAR1LMNANT5ESMN1; SMN2GLI1 | |
| SCHEMBL5442215 | 0.92 | GPBAR1 (0.64) | GPBAR1LMNANT5ESMN1; SMN2GLI1 | |
| SCHEMBL13351877 | 0.91 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| Lupane Anhydride SCHEMBL2133330 | 0.91 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| Lupane Anhydride SCHEMBL2141349 | 0.91 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| Lupane Anhydride SCHEMBL3525136 | 0.91 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| Lupane Anhydride SCHEMBL2135129 | 0.91 | GPBAR1 (0.54) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053817-A1 | BETULINIC ACID DERIVATIVES AND METHODS OF USE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2010-05-14 | — | — | WO | disclosed |