Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637193 | 0.86 | KMT2A (0.60) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL2845251 | 0.85 | HCAR2 (0.71) | ALDH1A1KMT2ASMN1; SMN2LTB4R | |
| SCHEMBL9973826 | 0.85 | KDM4E (0.70) | ALDH1A1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL14021040 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL20106688 | 0.83 | HCAR2 (0.56) | ALDH1A1KMT2AGAASMN1; SMN2CYP3A4 | |
| SCHEMBL14227339 | 0.82 | POLB (0.59) | ALDH1A1KMT2AHPGDMEN1GAA | |
| SCHEMBL16215170 | 0.82 | KDM4E (0.59) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL14227341 | 0.80 | POLB (0.57) | ALDH1A1KMT2AHPGDMEN1GAA | |
| SCHEMBL14227338 | 0.80 | HCAR2 (0.57) | ALDH1A1HPGDPOLBHDAC1HDAC2 | |
| SCHEMBL18760165 | 0.80 | NPC1 (0.67) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130497-A1 | Therapeutic Compounds | NFATC1, NAT1, AADAC | ALDH1A1 199/4885P2RX7 4200/4885KMT2A 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.