SCHEMBL13353447

SCHEMBL13353447

CC1(C)c2ccccc2N(c2ccc3c(c2)C(C)(C)c2cccc4c2N3c2ccccc2C4(C)C)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
PGR P06401 8/20 0.35
LMNA P02545 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HTT P42858 2/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
MAPT P10636 5/20 0.32
MEN1 O00255 4/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPK1 P28482 1/20 0.32
THRB P10828 2/20 0.30
RECQL P46063 2/20 0.30
GAA P10253 2/20 0.30
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13371106 0.94 PGR (0.36) KMT2ACYP1A2CYP2D6PGRLMNA
SCHEMBL13352804 0.92 MAPT (0.33) KMT2ACYP1A2CYP2D6PGRNPSR1
SCHEMBL13353446 0.90 HDAC6 (0.37) KMT2ACYP1A2CYP2D6PGRNPSR1
SCHEMBL13353419 0.90 TSHR (0.39) KMT2ACYP1A2CYP2D6PGRNPSR1
SCHEMBL13371104 0.90 TNKS (0.34) KMT2ACYP1A2CYP2D6PGRMEN1
SCHEMBL17804594 0.87 PGR (0.41) KMT2ACYP1A2CYP2D6PGRLMNA
SCHEMBL12281541 0.86 KMT2A (0.39) KMT2ACYP1A2CYP2D6PGRLMNA
SCHEMBL12333544 0.86 KMT2A (0.43) KMT2ACYP1A2CYP2D6PGRLMNA
SCHEMBL19267547 0.85 HTT (0.44) KMT2ACYP1A2CYP2D6LMNANPSR1
SCHEMBL12109082 0.85 KMT2A (0.36) KMT2ACYP1A2CYP2D6PGRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010050778-A1 NOVEL COMPOUNDS FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTRONIC DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2010-05-06 WO disclosed
EP-2182040-A2 Aromatic compounds and organic electronic device using the same Gracel Display Inc. (KR) 2010-05-05 EP disclosed