Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL1833685 | 0.93 | TDP1 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL1029320 | 0.93 | TDP1 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL2796966 | 0.90 | TDP1 (0.58) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL11491262 | 0.87 | TDP1 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL9738735 | 0.86 | CA12 (0.52) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28246814 | 0.84 | TDP1 (0.50) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28417451 | 0.84 | CA12 (0.50) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL11658010 | 0.82 | TDP1 (0.69) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL3417346 | 0.82 | CA2 (0.69) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL8710612 | 0.82 | TDP1 (0.69) | TDP1CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268590-B1 | SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS | SAINT GOBAIN ISOVER (FR) | 2018-06-13 | — | — | EP | claimed |
| EP-2268589-B1 | SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS | SAINT GOBAIN ISOVER (FR) | 2018-06-13 | — | — | EP | claimed |
| US-10233115-B2 | Formaldehyde-free sizing composition for fibres, in particular mineral fibres, and resulting products | SAINT-GOBAIN ISOVER (FR) | 2019-03-19 | — | — | US | disclosed |
| EP-2268590-B1 | SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS | SAINT GOBAIN ISOVER (FR) | 2018-06-13 | — | — | EP | disclosed |
| EP-2268589-B1 | SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS | SAINT GOBAIN ISOVER (FR) | 2018-06-13 | — | — | EP | disclosed |
| EP-2349944-B1 | PROCESS FOR MANUFACTURING INSULATION PRODUCTS BASED ON MINERAL WOOL, AND PRODUCTS OBTAINED | SAINT GOBAIN ISOVER (FR) | 2017-05-17 | — | — | EP | disclosed |
| CN-103702956-B | Formaldehyde-free sizing composition for fibres, in particular mineral fibres, and resulting products | 圣戈班伊索福公司 | 2017-05-17 | — | — | CN | disclosed |
| US-9630877-B2 | Sizing composition for fibers, in particular mineral fibers, based on humic and/or fulvic acid, and resulting insulating products | SAINT-GOBAIN ISOVER (FR) | 2017-04-25 | — | — | US | disclosed |
| US-9388071-B2 | Formaldehyde-free sizing composition for fibres, in particular mineral fibres, and resulting products | SAINT-GOBAIN ISOVER (FR) | 2016-07-12 | — | — | US | disclosed |
| US-20150203399-A1 | FORMALDEHYDE-FREE SIZING COMPOSITION FOR FIBRES, IN PARTICULAR MINERAL FIBRES, AND RESULTING PRODUCTS | SAINT-GOBAIN ISOVER (FR) | 2015-07-23 | — | — | US | disclosed |
| US-20140353539-A1 | SIZING COMPOSITION FOR FIBERS, IN PARTICULAR MINERAL FIBERS, BASED ON HUMIC AND/OR FULVIC ACID, AND RESULTING INSULATING PRODUCTS | SAINT-GOBAIN ISOVER (FR) | 2014-12-04 | — | — | US | disclosed |
| US-20140120348-A1 | FORMALDEHYDE-FREE SIZING COMPOSITION FOR FIBRES, IN PARTICULAR MINERAL FIBRES, AND RESULTING PRODUCTS | SAINT-GOBAIN ISOVER (FR) | 2014-05-01 | — | — | US | disclosed |
| US-20110272621-A1 | PROCESS FOR MANUFACTURING INSULATION PRODUCTS BASED ON MINERAL WOOL, AND PRODUCTS OBTAINED | SAINT-GOBAIN ISOVER (FR) | 2011-11-10 | — | — | US | disclosed |
| EP-2349944-A1 | PROCESS FOR MANUFACTURING INSULATION PRODUCTS BASED ON MINERAL WOOL, AND PRODUCTS OBTAINED | Saint-Gobain Isover (FR) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010040963-A1 | PROCESS FOR MANUFACTURING INSULATION PRODUCTS BASED ON MINERAL WOOL, AND PRODUCTS OBTAINED | SAINT-GOBAIN ISOVER (FR) | 2010-04-15 | — | — | WO | disclosed |