Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247193 | 0.93 | HTR6 (0.52) | HTR6HTR1ADRD2HTR7NCF1 | |
| SCHEMBL1247204 | 0.85 | HTR6 (0.60) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1250043 | 0.85 | HTR6 (0.54) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1249941 | 0.84 | HTR6 (0.46) | HTR6HTR1ADRD2HTR7HTR2A | |
| SCHEMBL1248616 | 0.83 | HTR6 (0.66) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1250176 | 0.82 | HTR6 (0.50) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1249789 | 0.82 | HTR6 (0.49) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1249743 | 0.82 | HTR6 (0.52) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1248579 | 0.82 | HTR6 (0.53) | HTR6HTR1ADRD2HTR7NCF1 | |
| SCHEMBL1249597 | 0.82 | HTR6 (0.52) | HTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056644-A1 | 1- (ARYLSULFONYL) -4- (PI PERAZIN-I -YL) -IH-BENZ IMIDAZOLES AS δ-HYDROXYTRYPTAMINE- 6 LIGANDS | WYETH LLC (US) | 2010-05-20 | — | — | WO | disclosed |