Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316272 | 0.85 | — | — | |
| SCHEMBL224972 | 0.78 | CA1 (0.32) | CA1CA2TSHRTDP1 | |
| SCHEMBL13104006 | 0.77 | — | — | |
| SCHEMBL4903359 | 0.77 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL8317472 | 0.76 | LMNA (0.42) | TSHRTDP1 | |
| SCHEMBL14003189 | 0.74 | TSHR (0.32) | TSHRTDP1 | |
| SCHEMBL223990 | 0.73 | — | — | |
| SCHEMBL13104225 | 0.73 | — | — | |
| SCHEMBL24052194 | 0.72 | — | — | |
| SCHEMBL18685324 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709515-B2 | Compositions comprising ether compounds and pharmaceutical uses therefor | ESPERION THERAPEUTICS, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-7192940-B2 | Ether compounds | ESPERION THERAPEUTICS, INC. (US) | 2007-03-20 | — | — | US | disclosed |