Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16919616 | 0.94 | SPHK1 (0.36) | SPHK1HTTMEN1KMT2AMAPT | |
| SCHEMBL16919617 | 0.94 | SPHK1 (0.36) | SPHK1HTTMEN1KMT2AMAPT | |
| SCHEMBL13354382 | 0.93 | SPHK1 (0.41) | SPHK1HTTMEN1KMT2AMAPT | |
| SCHEMBL13354512 | 0.93 | SPHK1 (0.35) | SPHK1HTTMEN1KMT2AMAPT | |
| SCHEMBL14979146 | 0.93 | SPHK1 (0.35) | SPHK1HTTMEN1KMT2AMAPT | |
| SCHEMBL30858317 | 0.81 | FFAR4 (0.42) | HTTMEN1KMT2AMAPTTHRB | |
| SCHEMBL16919597 | 0.80 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL16919596 | 0.80 | SPHK1 (0.31) | SPHK1 | |
| SCHEMBL13354587 | 0.79 | EPHX1 (0.44) | SPHK1HTTMAPTCYP2D6ADH1B | |
| SCHEMBL13354383 | 0.79 | SPHK1 (0.49) | SPHK1HTTMAPTCYP2D6ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |