Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 11/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16919615 | 0.84 | SPHK1 (0.36) | EPHX1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL16919616 | 0.84 | SPHK1 (0.36) | EPHX1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL16919617 | 0.84 | SPHK1 (0.36) | EPHX1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL12977945 | 0.81 | EPHX1 (0.48) | EPHX1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL13354383 | 0.81 | SPHK1 (0.49) | SPHK1ANPEPERAP2CYP2D6ADH1B | |
| SCHEMBL12977331 | 0.80 | SPHK1 (0.39) | EPHX1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL13354585 | 0.79 | SPHK1 (0.40) | SPHK1ANPEPERAP2CYP2D6ADH1B | |
| SCHEMBL13354518 | 0.79 | GGPS1 (0.38) | SPHK1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL16500375 | 0.79 | SPHK1 (0.38) | EPHX1SPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL25058924 | 0.77 | EPHX1 (0.61) | EPHX1SPHK1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |