Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355464 | 0.90 | CD38 (0.49) | CD38KMT2ALMNAFGFR3KDR | |
| SCHEMBL13355299 | 0.87 | CD38 (0.55) | CD38KMT2ALMNAFGFR3KDR | |
| SCHEMBL13355296 | 0.86 | CD38 (0.49) | CD38KMT2ALMNAFGFR3KDR | |
| SCHEMBL13355461 | 0.85 | CNR1 (0.46) | CD38KMT2AFGFR3KDRALDH1A1 | |
| SCHEMBL13355197 | 0.83 | KMT2A (0.50) | KMT2ALMNANAMPTCNR1TAAR1 | |
| SCHEMBL13355294 | 0.82 | KMT2A (0.47) | KMT2ALMNAFGFR3NOS1L3MBTL1 | |
| SCHEMBL13355295 | 0.81 | CNR1 (0.47) | CD38KMT2AFGFR3KDRALDH1A1 | |
| SCHEMBL25136362 | 0.78 | CD38 (0.72) | CD38KMT2ACYP3A4 | |
| SCHEMBL13355410 | 0.77 | KMT2A (0.55) | KMT2ALMNAALDH1A1NAMPTCNR1 | |
| SCHEMBL13355302 | 0.76 | NPC1 (0.48) | KMT2ALMNANOS2ALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |