Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355291 | 0.83 | CD38 (0.51) | KMT2ALMNACNR1MARS1TAAR1 | |
| SCHEMBL13355410 | 0.78 | KMT2A (0.55) | KMT2ALMNASMN1; SMN2MEN1HTT | |
| SCHEMBL13355294 | 0.77 | KMT2A (0.47) | KMT2ALMNASMN1; SMN2CNR1MARS1 | |
| SCHEMBL13355474 | 0.76 | KMT2A (0.53) | KMT2ALMNASMN1; SMN2MEN1CNR1 | |
| SCHEMBL13355293 | 0.76 | NPC1 (0.56) | KMT2ALMNASMN1; SMN2MEN1CNR1 | |
| SCHEMBL13355464 | 0.75 | CD38 (0.49) | KMT2ALMNACNR1MARS1TAAR1 | |
| SCHEMBL13355303 | 0.74 | HTR1A (0.51) | — | |
| SCHEMBL13355296 | 0.71 | CD38 (0.49) | KMT2ALMNASMN1; SMN2CNR1MARS1 | |
| SCHEMBL13355412 | 0.71 | NPC1 (0.49) | KMT2ALMNASMN1; SMN2MEN1CNR1 | |
| SCHEMBL4901058 | 0.70 | KMT2A (0.71) | KMT2ALMNASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |