Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 2/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355366 | 0.81 | ITGB3 (0.62) | CXCR4ITGAVITGB6ITGB3 | |
| SCHEMBL13355325 | 0.78 | CXCR4 (0.51) | CXCR4HTR7ALDH1A1ITGAVITGB3 | |
| SCHEMBL13355470 | 0.77 | ITGB3 (0.58) | CXCR4ITGAVITGB6ITGB3 | |
| SCHEMBL13355375 | 0.75 | ITGAV (0.57) | TSHRCXCR4ITGAVITGB6ITGB3 | |
| SCHEMBL13355417 | 0.74 | CXCR4 (0.63) | CXCR4ITGAVITGB6ITGB3 | |
| SCHEMBL3706122 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AALOX15TSHRPPARG | |
| SCHEMBL2639086 | 0.71 | PPARG (0.72) | SMN1; SMN2KMT2AALOX15TSHRPPARG | |
| SCHEMBL3138678 | 0.71 | ITGAV (0.54) | CXCR4ITGAVITGB6ITGB3 | |
| SCHEMBL2639089 | 0.71 | PPARG (0.72) | SMN1; SMN2KMT2AALOX15TSHRPPARG | |
| SCHEMBL30639808 | 0.71 | PPARG (0.72) | SMN1; SMN2KMT2AALOX15TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |