Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.53 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355388 | 0.88 | UHRF1 (0.43) | UHRF1NNMT | |
| SCHEMBL19033511 | 0.76 | UHRF1 (0.35) | UHRF1NNMTITGB3ITGAV | |
| SCHEMBL362637 | 0.73 | UHRF1 (0.38) | UHRF1NNMT | |
| SCHEMBL13693349 | 0.72 | NNMT (0.40) | UHRF1NNMT | |
| SCHEMBL4136886 | 0.70 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL14763953 | 0.70 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL29393274 | 0.70 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL30474583 | 0.69 | UHRF1 (0.53) | UHRF1NNMTITGB3ITGAV | |
| SCHEMBL279665 | 0.69 | UHRF1 (0.53) | UHRF1NNMTITGB3ITGAV | |
| SCHEMBL6325164 | 0.69 | UHRF1 (1.00) | UHRF1NNMTNPC1RAB9AIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057101-A2 | COMPOUNDS USEFUL AS HIV BLOCKERS | SCHERING CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |