Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 7/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093776 | 1.00 | KDM4E (0.46) | KDM4EHTTATMALDH1A1MEN1 | |
| SCHEMBL2878699 | 0.89 | KDM4E (0.49) | KDM4EHTTATMALDH1A1MEN1 | |
| SCHEMBL2876967 | 0.82 | KDM4E (0.46) | KDM4EHTTATMALDH1A1MAPT | |
| SCHEMBL2870751 | 0.82 | KDM4E (0.47) | KDM4EHTTATMALDH1A1MAPT | |
| SCHEMBL2876780 | 0.80 | CYP2E1 (0.43) | KDM4EHTTATMMAPTLMNA | |
| SCHEMBL320238 | 0.80 | CYP2E1 (0.57) | KDM4EHTTATMALDH1A1MAPT | |
| SCHEMBL320239 | 0.80 | CYP2E1 (0.57) | KDM4EHTTATMALDH1A1MAPT | |
| SCHEMBL14291007 | 0.78 | KDM4E (0.50) | KDM4EHTTATMALDH1A1MEN1 | |
| SCHEMBL2433933 | 0.78 | MAPT (0.43) | KDM4EHTTATMALDH1A1MEN1 | |
| SCHEMBL2433936 | 0.78 | MAPT (0.43) | KDM4EHTTATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | disclosed |