Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 14/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355910 | 1.00 | KDM4E (0.43) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL12306588 | 0.93 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL12306519 | 0.93 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL20232325 | 0.91 | KDM4E (0.43) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL20086970 | 0.91 | L3MBTL1 (0.47) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL21867570 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL14595508 | 0.90 | KDM4E (0.42) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL17808987 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1PDK2DUSP3 | |
| SCHEMBL12306589 | 0.90 | ATM (0.46) | KDM4EATML3MBTL1HDAC4PDK2 | |
| SCHEMBL17808983 | 0.89 | L3MBTL1 (0.41) | KDM4EATML3MBTL1PDK2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645552-B1 | Electroluminescent devices made with double-spiro organic compounds | LG CHEMICAL LTD (KR) | 2010-05-05 | — | — | EP | disclosed |