Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044635 | 0.84 | GAA (0.45) | SLC22A12ALDH1A1HTTLMNACNR2 | |
| SCHEMBL13862196 | 0.83 | ALDH1A1 (0.36) | SLC22A12ALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL3239637 | 0.81 | SLC22A12 (0.39) | SLC22A12ALDH1A1HTTLMNACNR2 | |
| SCHEMBL1043280 | 0.81 | CNR2 (0.42) | SLC22A12ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3246672 | 0.79 | CNR2 (0.38) | SLC22A12ALDH1A1SMN1; SMN2LMNACNR2 | |
| SCHEMBL1045768 | 0.78 | GAA (0.44) | SLC22A12ALDH1A1HTTLMNACNR2 | |
| SCHEMBL1041186 | 0.78 | GAA (0.45) | SLC22A12ALDH1A1HTTLMNACNR2 | |
| SCHEMBL1046376 | 0.77 | CNR2 (0.44) | SLC22A12ALDH1A1HTTLMNACNR2 | |
| SCHEMBL1044727 | 0.77 | CNR2 (0.44) | HTTLMNACNR2CMA1 | |
| SCHEMBL13862215 | 0.76 | ALDH1A1 (0.43) | SLC22A12ALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | disclosed |