Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043280 | 0.93 | CNR2 (0.42) | CNR2MAPTTP53POLBLMNA | |
| SCHEMBL1043213 | 0.89 | CNR2 (0.46) | CNR2MAPTTP53POLBLMNA | |
| SCHEMBL25725846 | 0.87 | CNR1 (0.51) | CNR2TP53CNR1TDP1HPGD | |
| SCHEMBL25725902 | 0.85 | CNR2 (0.43) | CNR2MAPTTP53POLBLMNA | |
| SCHEMBL3247125 | 0.85 | CNR2 (0.41) | CNR2MAPTTP53POLBLMNA | |
| SCHEMBL1046134 | 0.84 | CNR2 (0.50) | CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL1042951 | 0.83 | CNR1 (0.45) | CNR2LMNACNR1ALDH1A1HPGD | |
| SCHEMBL1042854 | 0.83 | LMNA (0.46) | CNR2MAPTTP53POLBLMNA | |
| SCHEMBL1046205 | 0.81 | KDM4E (0.54) | MAPTTP53POLBLMNATDP1 | |
| SCHEMBL1041186 | 0.81 | GAA (0.45) | CNR2LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | disclosed |