Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 9/20 | 0.46 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | MERTK | Q12866 | 2/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846271 | 0.92 | CDK1 (0.51) | HRH4ACP1APPBCHEACHE | |
| SCHEMBL3253575 | 0.88 | CDK1 (0.48) | HRH4ACP1APPBCHEACHE | |
| SCHEMBL3642691 | 0.82 | HRH4 (0.66) | HRH4ACP1APPPDE5ALMNA | |
| Hydrochloric Acid SCHEMBL3641028 | 0.81 | HRH4 (0.65) | HRH4ACP1PDE5ALMNAPOLB | |
| SCHEMBL20718973 | 0.81 | HRH4 (0.58) | HRH4APPBCHEACHEPDE5A | |
| SCHEMBL20733814 | 0.81 | HRH4 (0.58) | HRH4APPBCHEACHEPDE5A | |
| SCHEMBL2845074 | 0.81 | HRH4 (0.53) | HRH4APPBCHEACHEPDE5A | |
| SCHEMBL20718970 | 0.79 | CCNE2 (0.62) | HRH4APPPDE5APOLB | |
| SCHEMBL2852678 | 0.79 | HRH4 (0.51) | HRH4APPBCHEACHEPDE5A | |
| SCHEMBL20733875 | 0.78 | HRH4 (0.57) | HRH4APPBCHEACHEPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056907-A2 | COMPOUNDS THAT INDUCE PANCREATIC BETA-CELL EXPANSION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-05-20 | — | — | WO | disclosed |