Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846271 | 0.96 | CDK1 (0.51) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL2852678 | 0.93 | HRH4 (0.51) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL13356604 | 0.88 | HRH4 (0.52) | HRH4ACP1APPBCHEACHE | |
| SCHEMBL20733814 | 0.86 | HRH4 (0.58) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL20718973 | 0.86 | HRH4 (0.58) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL2845074 | 0.86 | HRH4 (0.53) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL20718970 | 0.84 | CCNE2 (0.62) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL20733875 | 0.84 | HRH4 (0.57) | CDK1HRH4CCNE2CCNE1CDK2 | |
| SCHEMBL3642691 | 0.78 | HRH4 (0.66) | HRH4ACP1APPHTR2ASLC2A1 | |
| Hydrochloric Acid SCHEMBL3641028 | 0.77 | HRH4 (0.65) | HRH4ACP1HTR2ASLC2A1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056907-A2 | COMPOUNDS THAT INDUCE PANCREATIC BETA-CELL EXPANSION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-05-20 | — | — | WO | claimed |