Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | VDR | P11473 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13324282 | 1.00 | GPBAR1 (0.66) | GPBAR1LMNAPOLBTRPV1CASP7 | |
| SCHEMBL16867284 | 1.00 | GPBAR1 (0.66) | GPBAR1LMNAPOLBTRPV1CASP7 | |
| SCHEMBL1236731 | 1.00 | GPBAR1 (0.66) | GPBAR1LMNAPOLBTRPV1CASP7 | |
| SCHEMBL6371803 | 0.89 | GPBAR1 (0.69) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL3192871 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL13324281 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL13324310 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL3192865 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL29618946 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 | |
| SCHEMBL16867281 | 0.87 | GPBAR1 (0.72) | GPBAR1LMNACASP7TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709666-B2 | Transgenic plants containing altered levels of sterol compounds and tocopherols | MONSANTO TECHNOLOGY LLC (US) | 2010-05-04 | — | — | US | disclosed |