SCHEMBL13358571

SCHEMBL13358571

CC1(C)c2cc(/C=C/c3ccc(N(c4cccc5ccccc45)c4cc5ccccc5c5ccccc45)cc3)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
USP2 O75604 1/20 0.32
CTNNB1 P35222 1/20 0.32
ATM Q13315 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
HSP90AA1 P07900 1/20 0.31
THRB P10828 1/20 0.31
XBP1 P17861 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13358296 1.00 APP (0.33) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13358295 0.99 APP (0.32) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13414140 0.96 S100A4 (0.33) MEN1ALDH1A1MAPTMAPK1KMT2A
SCHEMBL13358261 0.95 APP (0.36) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13414727 0.95 S100A4 (0.31) S100A4
SCHEMBL12887527 0.94 APP (0.37) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13371953 0.94 APP (0.34) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13414929 0.94 APP (0.37) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13358578 0.94 APP (0.37) APPMEN1ALDH1A1MAPTMAPK1
SCHEMBL13358408 0.94 APP (0.37) APPMEN1ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058995-A1 ELECTROLUMINESCENT DEVICE USING THE ELECTROLUMINESCENT COMPOUNDS GRACEL DISPLAY INC. (KR) 2010-05-27 WO disclosed
EP-2189508-A2 Electroluminescent device using electroluminescent compounds Gracel Display Inc. (KR) 2010-05-26 EP disclosed