SCHEMBL13359355

SCHEMBL13359355

O=Cc1ccc(C(=O)Oc2ccc(Cc3ccc(O)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.51
MAPT P10636 5/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48
MEN1 O00255 2/20 0.47
ELANE P08246 1/20 0.45
GFER P55789 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP3 Q9Y6F1 1/20 0.44
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
BCHE P06276 1/20 0.43
F2 P00734 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
ESR1 P03372 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12961702 1.00 KMT2A (0.51) KMT2AMAPTALDH1A1KDM4EALDH5A1
SCHEMBL18085607 0.91 MEN1 (0.56) KMT2AMAPTMEN1ELANEPARP10
SCHEMBL18025580 0.89 KMT2A (0.45) KMT2AMAPTALDH1A1KDM4EALDH5A1
SCHEMBL16938309 0.88 PARP10 (0.58) KMT2AMAPTALDH1A1KDM4EALDH5A1
SCHEMBL12961512 0.88 KMT2A (0.52) KMT2AMAPTALDH1A1KDM4EALDH5A1
SCHEMBL18078228 0.86 SRD5A2 (0.51) KMT2AMAPTALDH1A1KDM4EMEN1
SCHEMBL4243129 0.85 KMT2A (0.63) KMT2AMAPTALDH1A1KDM4EMEN1
SCHEMBL9400232 0.85 KMT2A (0.63) KMT2AMAPTALDH1A1KDM4EMEN1
SCHEMBL22065391 0.84 KMT2A (0.49) KMT2AMAPTALDH1A1KDM4EALDH5A1
SCHEMBL15855757 0.83 KMT2A (0.51) KMT2AMAPTALDH1A1KDM4EGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9235144-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-01-12 US disclosed
US-7718337-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-18 US disclosed
US-20090081570-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-26 US disclosed
US-7473507-B2 Electrophotographic photoreceptor with polyester resin in photosensitive layer MITSUBISHI CHEMICAL CORPORATION (JP) 2009-01-06 US disclosed
US-7244535-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-17 US disclosed