SCHEMBL4243129

SCHEMBL4243129

O=Cc1ccc(OC(=O)c2ccc(C=O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.63
MAPT P10636 5/20 0.63
ALDH1A1 P00352 4/20 0.63
KDM4E B2RXH2 3/20 0.63
PARP10 Q53GL7 2/20 0.56
PARP3 Q9Y6F1 1/20 0.56
GFER P55789 1/20 0.56
RAB9A P51151 1/20 0.54
HSD17B10 Q99714 1/20 0.53
F2 P00734 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
CYP2A6 P11509 1/20 0.48
GAA P10253 1/20 0.47
HGFAC Q04756 1/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9400232 1.00 KMT2A (0.63) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL27693913 0.93 ALDH1A1 (0.68) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL15500749 0.91 KMT2A (0.69) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL8009088 0.91 ALDH1A1 (0.58) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL15373867 0.91 ALDH1A1 (0.79) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL23169792 0.91 KMT2A (0.55) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL14513468 0.91 KMT2A (0.69) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL8613974 0.91 KMT2A (0.56) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL22826428 0.91 KMT2A (0.58) KMT2AMAPTALDH1A1KDM4EPARP10
SCHEMBL19218006 0.91 KMT2A (0.59) KMT2AMAPTALDH1A1KDM4EPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100259-B High-thermal-conductivity polyimide thermosetting resin containing aromatic ester structure and preparation method thereof 华南理工大学 2021-11-23 CN disclosed
CN-110229257-B Polymerizable monomer, curable composition, and resin member 德山齿科株式会社 2021-07-06 CN disclosed
EP-3187514-B1 POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER TOKUYAMA DENTAL CORP (JP) 2020-07-29 EP disclosed
CN-111100259-A High-thermal-conductivity polyimide thermosetting resin containing aromatic ester structure and preparation method thereof 华南理工大学 2020-05-05 CN disclosed
CN-106661153-B Polymerizable monomer, method for producing same, curable composition, and resin member 德山齿科株式会社 2019-11-08 CN disclosed
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER TOKUYAMA DENTAL CORPORATION (JP) 2019-10-03 US disclosed
CN-110229257-A Polymerizable monomer, solidification compound and resin component 德山齿科株式会社 2019-09-13 CN disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
EP-3187514-A1 POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER Tokuyama Dental Corporation (JP) 2017-07-05 EP disclosed
CN-106661153-A Polymerizable monomer, curable composition, and resin member 德山齿科株式会社 2017-05-10 CN disclosed
US-7521167-B2 Ester group-containing poly (imide-azomethine) copolymer, ester group-containing poly (amide acid-azomethine) copolymer, and positive photosensitive resin composition SONY CORPORATION (JP) 2009-04-21 US disclosed
US-7521167-B2 Ester group-containing poly (imide-azomethine) copolymer, ester group-containing poly (amide acid-azomethine) copolymer, and positive photosensitive resin composition SONY CORPORATION (JP) 2009-04-21 US disclosed
US-7521167-B2 Ester group-containing poly (imide-azomethine) copolymer, ester group-containing poly (amide acid-azomethine) copolymer, and positive photosensitive resin composition SONY CORPORATION (JP) 2009-04-21 US disclosed
US-20060269868-A1 Ester group-containing poly (imide-azomethine) copolymer, ester group-containing poly (amide acid-azomethine) copolymer, and positive photosensitive resin composition SONY CHEMICALS CORP. (JP) 2006-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 KMT2A 3675/4885MAPT 3773/4885ALDH1A1 3809/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 KMT2A 3866/4885MAPT 4098/4885ALDH1A1 4014/4885
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER CHRM1, CHRM2, H1-0 KMT2A 749/4885MAPT 972/4885ALDH1A1 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.