Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328243 | 0.89 | MEN1 (0.46) | MEN1KMT2ACA2TLR2 | |
| SCHEMBL13328241 | 0.87 | MEN1 (0.53) | MEN1KMT2ADPP4CA2POLB | |
| SCHEMBL13360298 | 0.85 | MEN1 (0.54) | MEN1KMT2ACA2TLR2 | |
| SCHEMBL21105478 | 0.83 | KMT2A (0.59) | MEN1KMT2ACA2POLB | |
| SCHEMBL22837635 | 0.83 | KMT2A (0.59) | MEN1KMT2ACA2POLB | |
| SCHEMBL21105932 | 0.83 | KMT2A (0.59) | MEN1KMT2ACA2POLB | |
| SCHEMBL25546667 | 0.83 | KMT2A (0.59) | MEN1KMT2ACA2POLB | |
| SCHEMBL7041313 | 0.82 | MEN1 (0.50) | MEN1KMT2ADPP4CA2POLB | |
| SCHEMBL24812863 | 0.80 | KMT2A (0.53) | MEN1KMT2APOLB | |
| SCHEMBL23945364 | 0.79 | MEN1 (0.46) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713944-B2 | Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |