Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 4/20 | 0.32 |
| ▸ | GLP1R | P43220 | 7/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328241 | 0.89 | MEN1 (0.53) | MEN1KMT2ACA2SMN1; SMN2TLR2 | |
| SCHEMBL22837635 | 0.88 | KMT2A (0.59) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL25546667 | 0.88 | KMT2A (0.59) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL21105932 | 0.88 | KMT2A (0.59) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL21105478 | 0.88 | KMT2A (0.59) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL13360295 | 0.85 | MEN1 (0.49) | MEN1KMT2ACA2TLR2 | |
| SCHEMBL24812863 | 0.84 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21106549 | 0.84 | MEN1 (0.54) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL25703724 | 0.84 | MEN1 (0.54) | MEN1KMT2ACA2SMN1; SMN2GLP1R | |
| SCHEMBL25110071 | 0.84 | MEN1 (0.54) | MEN1KMT2ACA2SMN1; SMN2GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713944-B2 | Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |