Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 3/20 | 0.32 |
| ▸ | GLP1R | P43220 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328241 | 0.86 | MEN1 (0.53) | MEN1KMT2ACA2DPP4DPP8 | |
| SCHEMBL21106192 | 0.85 | KMT2A (0.59) | MEN1KMT2ACES2CA2POLB | |
| SCHEMBL23568253 | 0.85 | KMT2A (0.59) | MEN1KMT2ACES2CA2POLB | |
| SCHEMBL23559968 | 0.85 | KMT2A (0.59) | MEN1KMT2ACES2CA2POLB | |
| SCHEMBL7300946 | 0.83 | MEN1 (0.58) | MEN1KMT2ACA2DPP4DPP8 | |
| SCHEMBL22375784 | 0.82 | MEN1 (0.49) | MEN1KMT2ACA2DPP4DPP8 | |
| SCHEMBL13029986 | 0.81 | MEN1 (0.47) | MEN1KMT2ACES2CA2DPP7 | |
| SCHEMBL25794016 | 0.81 | KMT2A (0.53) | MEN1KMT2ACES2POLBSMN1; SMN2 | |
| SCHEMBL24764090 | 0.81 | MEN1 (0.54) | MEN1KMT2ACES2CA2SMN1; SMN2 | |
| SCHEMBL19324447 | 0.80 | MEN1 (0.52) | MEN1KMT2ADPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713944-B2 | Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-11 | — | — | US | disclosed |