Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310889 | 0.91 | MEN1 (0.48) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL7298639 | 0.87 | MEN1 (0.51) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL26621066 | 0.84 | KMT2A (0.63) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL26059049 | 0.84 | KMT2A (0.63) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL8404642 | 0.84 | KMT2A (0.63) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL13360503 | 0.83 | MEN1 (0.54) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL7041313 | 0.83 | MEN1 (0.50) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL19324447 | 0.82 | MEN1 (0.52) | MEN1KMT2ADPP4FAPDPP8 | |
| SCHEMBL13328241 | 0.82 | MEN1 (0.53) | MEN1KMT2APOLBCA2SMN1; SMN2 | |
| SCHEMBL20086826 | 0.82 | MEN1 (0.50) | MEN1KMT2APOLBCA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | disclosed |