Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176435 | 0.88 | CYP3A4 (0.49) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL7263249 | 0.88 | CYP3A4 (0.49) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL9177023 | 0.88 | CYP3A4 (0.49) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL8752184 | 0.83 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL8752233 | 0.83 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL13360604 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2D6 | |
| SCHEMBL13714798 | 0.80 | HSP90AB1 (0.44) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL13714819 | 0.80 | HSP90AB1 (0.44) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL2606971 | 0.79 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 | |
| SCHEMBL20012285 | 0.78 | HPRT1 (0.45) | HSP90AB1HSP90AA1HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723319-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2010-05-25 | — | — | US | disclosed |
| US-20100004440-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | CHO DONG-GYU | 2010-01-07 | — | — | US | disclosed |
| US-7605147-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2009-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004440-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | PNP, ITPA, MTAP | HSP90AB1 3304/4885HSP90AA1 4081/4885HDAC1 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.