Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SRSF6 | Q13247 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14239433 | 1.00 | ADRB2 (0.66) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| SCHEMBL9970989 | 0.86 | ADRB2 (0.67) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL18946398 | 0.86 | ADRB2 (0.81) | ADRB2ADRB1 | |
| SCHEMBL14684192 | 0.86 | ADRB2 (0.66) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| SCHEMBL20730387 | 0.86 | ADRB2 (0.66) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| SCHEMBL14290919 | 0.85 | ADRB2 (0.70) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| SCHEMBL27936171 | 0.85 | ADRB2 (0.62) | ADRB2ADRB1SLC6A2ADRA1DHTR2A | |
| Hydrochloric Acid SCHEMBL11448321 | 0.85 | ADRB2 (0.69) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL4875051 | 0.83 | ADRB2 (0.70) | ADRB2ADRB1 | |
| SCHEMBL27950326 | 0.83 | ADRB2 (0.66) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113540-A1 | Azole and Thiazole Derivatives and Their Use | CHRM3, CHRM2, CHRM1 | ADRB2 108/4885ADRB1 47/4885SLC6A2 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.