SCHEMBL133638

SCHEMBL133638

CNC(=O)Nc1nc2ccccc2s1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.71
DYRK1A Q13627 1/20 0.71
NPC1 O15118 11/20 0.71
RAB9A P51151 11/20 0.71
SMN1; SMN2 Q16637 6/20 0.71
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
MAPT P10636 3/20 0.70
NFKB1 P19838 3/20 0.70
NFKB2 Q00653 3/20 0.70
RELA Q04206 3/20 0.70
GAA P10253 2/20 0.70
ACP1 P24666 1/20 0.65
ALDH1A1 P00352 4/20 0.61
PKM P14618 1/20 0.60
PAX8 Q06710 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
LMNA P02545 2/20 0.60
POLB P06746 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534896 1.00 ADORA1 (0.71) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL27634788 0.90 NPC1 (0.84) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL32674581 0.90 NPC1 (0.84) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL9160858 0.84 NPC1 (0.70) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL3283083 0.83 DYRK1A (1.00) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL161765 0.83 NPC1 (0.66) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL6228486 0.83 NPC1 (0.66) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL1842324 0.83 NPC1 (1.00) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL11712929 0.83 NPC1 (0.73) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL1143751 0.83 NPC1 (1.00) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5619 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20240130368-A1 HERBICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-04-25 US claimed
WO-2024084471-A1 SAFLUFENACIL MICROEMULSION COMPOSITION, METHOD FOR THE PREPARATION THEREOF AND USE OF SAME DVA AGRO GMBH (DE) 2024-04-25 WO claimed
EP-4316244-A1 HERBICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-02-07 EP claimed
CN-116867373-A Herbicidal composition 日本曹达株式会社 2023-10-10 CN claimed
US-20230247988-A1 HERBICIDE COMBINATIONS UPL LTD (IN) 2023-08-10 US claimed
CN-116385673-A Three-dimensional scene roaming system and method based on GIS 河北志晟信息技术股份有限公司 2023-07-04 CN claimed
WO-2000062792-A2 COMPOSITIONS AND METHODS FOR CONTROLLING PESTS INSECT BIOTECHNOLOGY, INC. (US) 2000-10-26 WO claimed
CN-1259013-A Herbicidal compositions ISAGRO RICERCA SRL (IT) 2000-07-05 CN claimed
EP-0986303-A1 HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.r.l. (IT) 2000-03-22 EP claimed
WO-1998054967-A1 HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 1998-12-10 WO claimed
EP-0859548-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1998-08-26 EP claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
WO-1997010714-A1 HERBICIDAL MIXTURES HAVING A SYNERGISTIC EFFECT BASF AKTIENGESELLSCHAFT (DE) 1997-03-27 WO claimed
EP-0390394-A2 Composition and use ZENECA LIMITED (GB) 1990-10-03 EP claimed
EP-0180313-A1 Triazole or imidazole fungicide compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-05-07 EP claimed
US-4004913-A IMIDAZOLIDIN-2-ONE-1-CARBOXYLIC ACID ISOBUTYLAMIDE, 1-METHYL-3-(2-BENZOTHIAZOLYL)UREA BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US claimed