Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 11/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.70 |
| ▸ | RELA | Q04206 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | ACP1 | P24666 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133638 | 1.00 | ADORA1 (0.71) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27634788 | 0.90 | NPC1 (0.84) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL32674581 | 0.90 | NPC1 (0.84) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9160858 | 0.84 | NPC1 (0.70) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3283083 | 0.83 | DYRK1A (1.00) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL161765 | 0.83 | NPC1 (0.66) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6228486 | 0.83 | NPC1 (0.66) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1842324 | 0.83 | NPC1 (1.00) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11712929 | 0.83 | NPC1 (0.73) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1143751 | 0.83 | NPC1 (1.00) | ADORA1DYRK1ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |