SCHEMBL1336592

SCHEMBL1336592

O=C1CN=CC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29828683 0.97
SCHEMBL4875489 0.71
SCHEMBL3686601 0.65
SCHEMBL22237561 0.65
SCHEMBL993545 0.61
SCHEMBL7277052 0.59
SCHEMBL72400 0.58
SCHEMBL2139113 0.57
SCHEMBL3870589 0.56
SCHEMBL1199564 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604494-A PCSK9 inhibitors and methods of use thereof 阿斯利康(瑞典)有限公司 2025-03-11 CN claimed
CN-117729916-A Benzodioxane modulators of leukotriene A4 hydrolase (LTA 4H) for the prevention and treatment of aging-related diseases 万能溶剂有限公司 2024-03-19 CN claimed
CN-115151534-B Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof 南京药石科技股份有限公司 2024-02-06 CN claimed
CN-115315424-A 2-methyl-aza-quinazolines 拜耳公司 2022-11-08 CN claimed
CN-115151534-A Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof 南京药石科技股份有限公司 2022-10-04 CN claimed
WO-2021159993-A1 INHIBITORS OF INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE (IRAK) /FMS-LIKE RECEPTOR TYROSINE KINASE (FLT3), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF PHARMABLOCK SCIENCES (NANJING) , INC. (CN) 2021-08-19 WO claimed
WO-2020071550-A1 CDK8 INHIBITOR AND USE OF SAME 京都薬品工業株式会社 2020-04-09 WO claimed
CN-105968054-A Preparation of pimobendan key intermediate 海门慧聚药业有限公司 2016-09-28 CN claimed
CN-105555786-A Substituted dihydropyrido [3,4-b ] pyrazinones as dual inhibitors of BET proteins and polo-like kinases Bayer Pharma AG 2016-05-04 CN claimed
CN-103991942-B The treatment process of chlorophenols Micropollutants in a kind of water body UNIVERSITY OF SCIENCE AND TECHNOLOGY OF SUZHOU (CN) 2015-12-30 CN claimed
WO-2015193229-A1 BET-PROTEIN INHIBITING 1,4-DIHYDROPYRIDO[3,4-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2015-12-23 WO claimed
CN-104987310-A Synthesis process of levosimendan UNIV QINGDAO AGRICULTURAL 2015-10-21 CN claimed
CN-102341394-B Poly (ADP-Ribose) Polymerase (PARP) Inhibitors TAKEDA PHARMACEUTICAL 2015-04-15 CN claimed
EP-0920429-A1 SUBSTITUTED PYRIDO- OR PYRIMIDO-CONTAINING 6,6- OR 6,7-BICYCLIC DERIVATIVES PFIZER INC. (US) 1999-06-09 EP claimed
WO-1998005661-A1 SUBSTITUTED PYRIDO- OR PYRIMIDO-CONTAINING 6,6- OR 6,7-BICYCLIC DERIVATIVES PFIZER INC. (US) 1998-02-12 WO claimed
EP-0814808-A1 PHARMACEUTICAL, COSMETIC AND/OR FOOD COMPOSITION HAVING ANTI-OXIDANT PROPERTIES UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 1998-01-07 EP claimed
WO-1996028160-A1 PHARMACEUTICAL, COSMETIC AND/OR FOOD COMPOSITION HAVING ANTI-OXIDANT PROPERTIES UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 1996-09-19 WO claimed
WO-1995029255-A1 LUMINESCENCE-BASED DIAGNOSTICS MEDILITE DIAGNOSTIKA (US) 1995-11-02 WO claimed
CN-122070282-A Pyrazole-1-carboxamides as RIP1 kinase inhibitors 比西切姆有限公司 2026-05-19 CN disclosed
WO-1995029255-A1 LUMINESCENCE-BASED DIAGNOSTICS MEDILITE DIAGNOSTIKA (US) 1995-11-02 WO disclosed