Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 10/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.43 |
| ▸ | IGF1R | P08069 | 5/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928658 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL18711174 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL18711250 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL18711179 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL18711226 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL19928684 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL18711177 | 0.72 | PIM1 (0.42) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL13779496 | 0.70 | PIM1 (0.53) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL680731 | 0.70 | PIM1 (0.53) | PIM1PIM2IGF1RAKR1B1NPC1 | |
| SCHEMBL13340886 | 0.70 | PIM1 (0.53) | PIM1PIM2IGF1RAKR1B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058402-A1 | NOVEL ANTI-BIOFILM AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-05-27 | — | — | WO | disclosed |