⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070 | 0.74 | — | — | |
| SCHEMBL9042428 | 0.72 | — | — | |
| SCHEMBL2105846 | 0.72 | — | — | |
| SCHEMBL15511209 | 0.72 | — | — | |
| SCHEMBL1335384 | 0.72 | — | — | |
| SCHEMBL6419511 | 0.72 | — | — | |
| SCHEMBL93261 | 0.72 | — | — | |
| SCHEMBL3042086 | 0.70 | — | — | |
| SCHEMBL3404119 | 0.70 | — | — | |
| SCHEMBL93253 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965591-A | MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 1999-10-12 | — | — | US | claimed |
| US-4465632-A | Process for preparing 1-6-and 2-substituted-1-carba-2-penem-3-carboxylic acids | MERCK & CO., INC. (US) | 1984-08-14 | — | — | US | claimed |
| US-4348320-A | PENICILLIN INTERMEDIATES | MERCK & CO., INC. (US) | 1982-09-07 | — | — | US | claimed |
| US-4235922-A | THIENAMYCIN DERIVATIVES | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | claimed |
| US-4146633-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1979-03-27 | — | — | US | claimed |
| EP-1757609-B1 | NOVEL WATER-SOLUBLE PRODRUG | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-8470829-B2 | Imidazolidine derivative and use thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2013-06-25 | — | — | US | disclosed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-20110306615-A1 | NOVEL IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-12-15 | — | — | US | disclosed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-8022047-B2 | Combination anticancer agents | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-09-20 | — | — | US | disclosed |
| US-7910593-B2 | Water-soluble prodrugs | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-03-22 | — | — | US | disclosed |
| EP-0010316-A1 | 1-, 6- and 2-substituted-1-carba-2-penem-3-carboxylic acids, process for preparing the same and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4146633-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1979-03-27 | — | — | US | disclosed |