⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070 | 0.74 | — | — | |
| SCHEMBL15511209 | 0.72 | — | — | |
| SCHEMBL1336710 | 0.72 | — | — | |
| SCHEMBL5710998 | 0.72 | — | — | |
| SCHEMBL9042428 | 0.72 | — | — | |
| SCHEMBL6419511 | 0.72 | — | — | |
| SCHEMBL1335384 | 0.72 | — | — | |
| SCHEMBL93261 | 0.72 | — | — | |
| SCHEMBL10610686 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL3042086 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | claimed |
| US-7456279-B2 | Coupling process for preparing quinolone intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2008-11-25 | — | — | US | claimed |
| US-20070232804-A1 | Coupling process for preparing quinolone intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-04 | — | — | US | claimed |
| CN-115960159-A | Automatic change polypeptide synthesizer of non-maintaining amino acid delivery route | 希施生物科技（上海）有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |
| US-8158798-B2 | Coupling process for preparing quinolone intermediates | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-04-17 | — | — | US | disclosed |
| US-20090111991-A1 | Coupling Process For Preparing Quinolone Intermediates | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2009-04-30 | — | — | US | disclosed |
| EP-1999125-A2 | A COUPLING PROCESS FOR PREPARING QUINOLONE INTERMEDIATES | The Procter and Gamble Company (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7456279-B2 | Coupling process for preparing quinolone intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070232804-A1 | Coupling process for preparing quinolone intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007110835-A2 | A COUPLING PROCESS FOR PREPARING QUINOLONE INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-04 | — | — | WO | disclosed |
| US-5646120-A | OLIGO- AND POLYARGININE AND DERIVATIVES | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1997-07-08 | — | — | US | disclosed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5625030-A | ESTERIFICATION OF HYDROXY ACIDS JOINED TO SUPPORT, PROTECTING AND DEPROTECTING | METABOLIX, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0675898-A1 | USE OF MOLECULARLY IMPRINTED POLYMERS FOR STEREO- AND/OR REGIOSELECTIVE SYNTHESIS | MOSBACH, Klaus H. (SE) | 1995-10-11 | — | — | EP | disclosed |
| WO-1995018781-A1 | METHODS FOR SYNTHESIZING OLIGOMERS CONTAINING HYDROXY ACID UNITS | METABOLIX, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| WO-1994014835-A1 | USE OF MOLECULARLY IMPRINTED POLYMERS FOR STEREO- AND/OR REGIOSELECTIVE SYNTHESIS | MOSBACH KLAUS (SE) | 1994-07-07 | — | — | WO | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |