SCHEMBL1336714

SCHEMBL1336714

Nc1ccccc1Nc1ccc(F)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.70
KDM4E B2RXH2 4/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
TP53 P04637 1/20 0.70
APP P05067 1/20 0.70
HPGD P15428 1/20 0.70
ALOX15 P16050 1/20 0.70
SNCA P37840 1/20 0.70
BLM P54132 1/20 0.70
HSD17B10 Q99714 1/20 0.70
GAA P10253 6/20 0.69
ALDH1A1 P00352 5/20 0.69
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
LMNA P02545 1/20 0.69
CYP1A2 P05177 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
TDP1 Q9NUW8 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414661 1.00 MAPT (0.70) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL3980084 0.89 MAPT (0.61) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL4607773 0.89 MAPT (0.86) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL6651517 0.87 MAPK13 (0.79) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL17382717 0.84 MAPT (0.53) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL1636651 0.83 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL9396738 0.83 MAPT (0.91) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL4647245 0.83 MAPT (0.76) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL217480 0.82 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL29388147 0.82 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700021-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Sapiensbio Inc. (KR) 2026-02-25 EP disclosed
EP-4538270-A1 NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Sapiensbio Inc. (KR) 2025-04-16 EP disclosed
WO-2023239227-A1 NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 사피엔스바이오 2023-12-14 WO disclosed
CN-111747933-B Substituted 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2022-03-01 CN disclosed
CN-111747937-B 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2022-01-14 CN disclosed
CN-111747936-B Substituted 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2021-10-22 CN disclosed
CN-111747936-A Substituted 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2020-10-09 CN disclosed
CN-111747933-A Substituted 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2020-10-09 CN disclosed
CN-111747937-A 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2020-10-09 CN disclosed
WO-2020199998-A1 1,3,5-TRIAZINE COMPOUND AND COMPOSITION, AND APPLICATION THEREOF 吉林省元合电子材料有限公司 2020-10-08 WO disclosed
US-5580895-A GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS GLAXO SPA (IT) 1996-12-03 US disclosed
US-5486514-A GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS GLAXO SPA (IT) 1996-01-23 US disclosed
EP-0623118-A1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO S.p.A. (IT) 1994-11-09 EP disclosed
CN-1077952-A CARBAMATE DERIVATIVES GLAXO SPA (IT) 1993-11-03 CN disclosed
EP-0356176-B1 ACETAMIDE COMPOUNDS HAMARI YAKUHIN KOGYO KABUSHIKI KAISHA also known as HAMARI CHEMICALS, LTD. (JP) 1993-09-22 EP disclosed
EP-0558104-A1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO S.p.A. (IT) 1993-09-01 EP disclosed
CN-1074678-A 1, the 5-benzodiazepine derivatives GLAXO SPA (IT) 1993-07-28 CN disclosed
WO-1993014075-A1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO SPA (IT) 1993-07-22 WO disclosed
US-4950667-A Pyridinyl acetamide compounds useful in treating ulcers HAMARI CHEMICALS, LTD. (JP) 1990-08-21 US disclosed
EP-0356176-A1 Acetamide compounds HAMARI YAKUHIN KOGYO KABUSHIKI KAISHA also known as HAMARI CHEMICALS, LTD. (JP) 1990-02-28 EP disclosed