SCHEMBL4607773

SCHEMBL4607773

Nc1ccccc1Nc1ccc(Nc2ccccc2N)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.86
KDM4E B2RXH2 5/20 0.86
SMN1; SMN2 Q16637 2/20 0.86
TP53 P04637 1/20 0.86
APP P05067 1/20 0.86
HPGD P15428 1/20 0.86
ALOX15 P16050 1/20 0.86
SNCA P37840 1/20 0.86
BLM P54132 1/20 0.86
HSD17B10 Q99714 1/20 0.86
GAA P10253 6/20 0.86
ALDH1A1 P00352 6/20 0.86
MEN1 O00255 4/20 0.86
KMT2A Q03164 4/20 0.86
CYP1A2 P05177 2/20 0.86
CYP2C9 P11712 2/20 0.86
CYP2C19 P33261 2/20 0.86
LMNA P02545 1/20 0.86
CYP2D6 P10635 1/20 0.86
TDP1 Q9NUW8 3/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636651 0.93 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL9396738 0.93 MAPT (0.91) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL4647245 0.93 MAPT (0.76) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL217480 0.92 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL29388147 0.92 MAPT (1.00) MAPTKDM4ESMN1; SMN2TP53APP
Methane SCHEMBL28002603 0.91 MAPT (0.96) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL6576141 0.90 MAPT (0.95) MAPTKDM4ESMN1; SMN2TP53APP
Methane SCHEMBL4054340 0.90 MAPT (0.95) MAPTKDM4ESMN1; SMN2TP53APP
Hydrochloric Acid SCHEMBL29809096 0.90 MAPT (0.95) MAPTKDM4ESMN1; SMN2TP53APP
SCHEMBL1336714 0.89 MAPT (0.70) MAPTKDM4ESMN1; SMN2TP53APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310522-B1 CROSSLINKABLE ELASTOMER COMPOSITION DAIKIN IND LTD (JP) 2008-07-23 EP disclosed
US-6855774-B2 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2005-02-15 US disclosed
US-20030191247-A1 Crosslinkable elastomer composition DAIKIN INDUSTRIES, LTD. (JP) 2003-10-09 US disclosed
EP-1310522-A1 CROSSLINKABLE ELASTOMER COMPOSITION Daikin Industries, Ltd. (JP) 2003-05-14 EP disclosed
US-5554715-A DI/HYDROXYPHENYL-N-ARYLENEBENZIMIDAZOLES/ USED AS MONOMERS IN THE DISPLACEMENT REACTION ARE CLAIMED. THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1996-09-10 US disclosed
US-5410012-A Poly(N-arylenebenzimidazoles) via aromatic nucleophilic displacement THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1995-04-25 US disclosed
US-4154919-A CONDENSED FROM DIANHYDRIDE AND A TETRAAMINE, MINIMAL SOFTENING AND BURNING AT HIGH TEMPERATURE ACUREX CORPORATION (US) 1979-05-15 US disclosed