Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299438 | 0.85 | TP53 (0.67) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL1171070 | 0.85 | TP53 (0.67) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL542855 | 0.85 | TP53 (0.67) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL511872 | 0.85 | TP53 (0.67) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL14648856 | 0.84 | TP53 (0.60) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL19359219 | 0.84 | TP53 (0.60) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL12284244 | 0.84 | TP53 (0.60) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL1927731 | 0.84 | TP53 (0.60) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL12284622 | 0.84 | TP53 (0.60) | TP53ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL19359544 | 0.84 | ALDH1A1 (0.63) | TP53ALDH1A1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056778-A1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES, INC. (US) | 2010-05-20 | — | — | WO | disclosed |