Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | PCNA | P12004 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27268576 | 0.97 | ITGB3 (0.50) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL27268088 | 0.97 | ITGB3 (0.50) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL27268584 | 0.97 | ITGB3 (0.50) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL9023346 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL9023343 | 0.92 | ITGB3 (0.47) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL12801826 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL14051416 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL8246768 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL27268862 | 0.88 | ACACB (0.51) | ITGB3ITGA2BACACBATMHDAC8 | |
| SCHEMBL27268361 | 0.87 | ACACB (0.50) | ITGB3ITGA2BACACBATMHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |