Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.61 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26250622 | 1.00 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL18244437 | 0.97 | ITGB3 (0.58) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL27268563 | 0.97 | ITGB3 (0.58) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL27268543 | 0.97 | ITGB3 (0.58) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL18244438 | 0.97 | ITGB3 (0.58) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL27268078 | 0.97 | ITGB3 (0.58) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL9483916 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL9483923 | 0.92 | ITGB3 (0.55) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL15593763 | 0.91 | ITGB3 (0.64) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL4937967 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |