Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10152017 | 0.86 | MAOA (0.54) | MAOAF10CALML3MAOB | |
| SCHEMBL10152018 | 0.84 | MAOA (0.44) | MAOAF10CALML3MAOB | |
| SCHEMBL13367951 | 0.83 | MAOA (0.44) | MAOAF10CALML3MAOB | |
| SCHEMBL14863432 | 0.80 | MAOA (0.44) | GRM2MAOAF10CALML3 | |
| SCHEMBL14863433 | 0.80 | MAOA (0.44) | GRM2MAOAF10CALML3 | |
| SCHEMBL10152022 | 0.79 | MAOA (0.51) | MAOAF10CALML3MAOB | |
| SCHEMBL14862023 | 0.78 | MAOA (0.50) | GRM2MAOAF10CALML3MAOB | |
| SCHEMBL14862026 | 0.78 | MAOA (0.50) | GRM2MAOAF10CALML3MAOB | |
| SCHEMBL13981113 | 0.77 | MAOA (0.48) | MAOAF10CALML3MAOB | |
| SCHEMBL10152023 | 0.77 | MAOA (0.42) | MAOAF10CALML3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181993-A1 | Antimicrobial oxazolidinone derivatives | Research Foundation Itsuu Laboratory (JP) | 2010-05-05 | — | — | EP | disclosed |