Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368170 | 0.92 | KCNH2 (0.35) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14014256 | 0.83 | STAT3 (0.42) | STAT3CYP3A4CYP2C19KDM4EKCNH2 | |
| SCHEMBL13341768 | 0.83 | STAT3 (0.42) | STAT3CYP3A4CYP2C19KDM4EKCNH2 | |
| SCHEMBL13341766 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C19KDM4EKCNH2ALDH1A1 | |
| SCHEMBL14014253 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C19KDM4EKCNH2ALDH1A1 | |
| SCHEMBL3578342 | 0.74 | MEN1 (0.35) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13368174 | 0.73 | SCN5A (0.47) | CYP3A4KCNH2ALDH1A1 | |
| SCHEMBL17494299 | 0.73 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL13368169 | 0.71 | CYP1A2 (0.57) | STAT3CYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL13968307 | 0.70 | CYP2C19 (0.40) | CYP1A2CYP3A4CYP2C19KDM4ECLEC4M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723524-B2 | 8-cyanoquinolonecarboxylic acid derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |