Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590136 | 0.86 | CYP3A4 (0.35) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3577931 | 0.78 | KCNH2 (0.33) | ALDH1A1DRD2DRD3POLBKDM4E | |
| SCHEMBL3575973 | 0.77 | CYP3A4 (0.42) | SMN1; SMN2DRD2 | |
| SCHEMBL17494299 | 0.76 | KCNH2 (0.58) | — | |
| SCHEMBL13368166 | 0.74 | STAT3 (0.38) | MEN1KMT2AMAPTALDH1A1BTK | |
| SCHEMBL4510781 | 0.71 | DRD2 (0.43) | DRD2DRD3OPRK1 | |
| SCHEMBL14014256 | 0.71 | STAT3 (0.42) | ALDH1A1BTKPOLBKDM4EHPGD | |
| SCHEMBL13341768 | 0.71 | STAT3 (0.42) | ALDH1A1BTKPOLBKDM4EHPGD | |
| SCHEMBL4501494 | 0.70 | ACACB (0.41) | MAPTALDH1A1DRD2DRD3 | |
| SCHEMBL19194882 | 0.69 | KCNH2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7626029-B2 | Into a difluorobenzoic acid, for producting quinolonecarboxylic acid serving as synthetic antibacterial agent, medicament, agricultural chemical, or veterinary drug; ionic liquid solvents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060122396-A1 | Method of selectively introducing amino substituent | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122396-A1 | Method of selectively introducing amino substituent | ASNS, NQO2, DDC | MEN1 4072/4885KMT2A 1571/4885MAPT 4808/4885 |
| US-20100069435-A1 | METHOD OF SELECTIVELY INTRODUCING AMINO SUBSTITUENT | ASNS, DDC, NQO2 | MEN1 3971/4885KMT2A 1549/4885MAPT 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.