Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964315 | 0.92 | HTR6 (0.64) | HTR6RORCLMNATSHRMAPK1 | |
| SCHEMBL14262775 | 0.89 | HTR6 (0.74) | HTR6SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13368589 | 0.88 | HTR6 (0.57) | HTR6MAPTRORCLMNATSHR | |
| SCHEMBL13964852 | 0.87 | HTR6 (0.56) | HTR6MAPTRORCLMNATSHR | |
| SCHEMBL13240261 | 0.86 | HTR6 (0.61) | HTR6SMN1; SMN2MAPTRORCLMNA | |
| SCHEMBL14468638 | 0.85 | HTR6 (0.58) | HTR6SMN1; SMN2MAPTRORCCYP3A4 | |
| SCHEMBL13964682 | 0.83 | HTR6 (0.66) | HTR6SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13964793 | 0.83 | HTR6 (0.60) | HTR6MAPTMEN1KMT2ALMNA | |
| SCHEMBL13368595 | 0.83 | HTR6 (0.57) | HTR6MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL13964695 | 0.82 | HTR6 (0.54) | HTR6SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723374-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2010-05-25 | — | — | US | disclosed |