Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 18/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094686 | 0.83 | CCR9 (0.63) | CCR9HSD17B2 | |
| SCHEMBL13343559 | 0.80 | CCR9 (0.55) | CCR9 | |
| SCHEMBL1095568 | 0.80 | CCR9 (0.54) | CCR9HSD17B2 | |
| SCHEMBL1095424 | 0.79 | CCR9 (0.59) | CCR9HSD17B2 | |
| SCHEMBL1095266 | 0.79 | CCR9 (0.59) | CCR9HSD17B2 | |
| SCHEMBL1093878 | 0.79 | CCR9 (0.56) | CCR9 | |
| SCHEMBL1094478 | 0.79 | CCR9 (0.56) | CCR9 | |
| SCHEMBL1094053 | 0.78 | CCR9 (0.57) | CCR9 | |
| SCHEMBL1093732 | 0.78 | CCR9 (0.51) | CCR9 | |
| SCHEMBL1093996 | 0.78 | CCR9 (0.51) | CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718683-B2 | Triazolyl phenyl benzenesulfonamides | CHEMOCENTRYX, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080039465-A1 | TRIAZOLYL PHENYL BENZENESULFONAMIDES | CHEMOCENTRYX, INC. | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039465-A1 | TRIAZOLYL PHENYL BENZENESULFONAMIDES | CCR9, CCR2, CCR1 | CCR9 1/4885HSD17B2 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.