Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627487 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL17988744 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL19308094 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL9245414 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL3626104 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL10658454 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL26983691 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL276714 | 0.97 | ALDH1A1 (0.61) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL24684882 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TDP1LMNAOPRM1DNM1 | |
| SCHEMBL20495968 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TDP1LMNAOPRM1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113696-A | Gene editing to improve joint function | 奥泽生物疗法公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3124551-A1 | RHODAMINE-BASED COLORING COMPOSITION | Wako Pure Chemical Industries, Ltd. (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-7723345-B2 | Multicyclic amino acid derivatives and methods of their use | LEXICON PHARMACEUTICALS, INC. (US) | 2010-05-25 | — | — | US | disclosed |