SCHEMBL13370868

SCHEMBL13370868

COc1cccc(C(=O)N2[C@@H](C(=O)O)CC[C@@H]2c2ccccc2Cl)c1.COc1cccc(C(=O)N2[C@@H](C(=O)O)CC[C@H]2c2ccccc2Cl)c1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 19/20 0.84
HTT P42858 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788351 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL29787755 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL19406596 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL29787764 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL2039477 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL2046155 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL2034950 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL2037507 1.00 FFAR2 (0.84) FFAR2HTT
SCHEMBL21313724 0.94 FFAR2 (0.87) FFAR2
SCHEMBL29787612 0.94 FFAR2 (0.87) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513053-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43) Euroscreen S.A. (BE) 2012-10-24 EP claimed