Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 4/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | ATP4A | P20648 | 4/20 | 0.42 |
| ▸ | ATP4B | P51164 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283662 | 0.93 | AGER (0.67) | AGERHRH3ATP4AATP4BDRD2 | |
| SCHEMBL14639926 | 0.91 | AGER (0.54) | AGERHRH3ATP4AATP4BDRD2 | |
| SCHEMBL1615394 | 0.85 | AGER (0.65) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283911 | 0.82 | AGER (0.63) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283433 | 0.82 | AGER (0.63) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283339 | 0.82 | AGER (0.63) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283410 | 0.80 | AGER (0.65) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283367 | 0.80 | AGER (0.84) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283226 | 0.79 | AGER (0.64) | AGERHRH3ATP4AATP4B | |
| SCHEMBL1283596 | 0.78 | AGER (0.62) | AGERHRH3ATP4AATP4BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714013-B2 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. (US) | 2010-05-11 | — | — | US | disclosed |