Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | AGER | Q15109 | 11/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283150 | 0.98 | DRD3 (0.50) | DRD3DRD2AGERCASR | |
| SCHEMBL1283630 | 0.90 | DRD2 (0.46) | DRD3DRD2AGER | |
| SCHEMBL1615182 | 0.90 | DRD3 (0.52) | DRD3DRD2AGERCASR | |
| SCHEMBL1283146 | 0.90 | DRD3 (0.57) | DRD3DRD2AGER | |
| SCHEMBL1283718 | 0.89 | DRD2 (0.44) | DRD3DRD2AGERCASR | |
| SCHEMBL1282827 | 0.89 | DRD3 (0.50) | DRD3DRD2AGERCASR | |
| SCHEMBL1282883 | 0.88 | DRD3 (0.55) | DRD3DRD2AGERCASR | |
| SCHEMBL1282844 | 0.88 | DRD3 (0.56) | DRD3DRD2AGER | |
| SCHEMBL1283251 | 0.87 | DRD3 (0.47) | DRD3DRD2AGERCASR | |
| SCHEMBL1283201 | 0.87 | DRD3 (0.48) | DRD3DRD2AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714013-B2 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. (US) | 2010-05-11 | — | — | US | disclosed |