Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.46 |
| ▸ | PGR | P06401 | 13/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13372614 | 1.00 | AR (0.46) | ARPGRNR3C2NR3C1PDE4D | |
| SCHEMBL923848 | 0.88 | AR (0.48) | ARPGRNR3C2NR3C1PDE4D | |
| SCHEMBL923996 | 0.88 | AR (0.48) | ARPGRNR3C2NR3C1PDE4D | |
| SCHEMBL13372689 | 0.87 | AR (0.48) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL13372615 | 0.87 | AR (0.48) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL16564526 | 0.82 | AR (0.46) | ARPGRNR3C2NR3C1PDE4D | |
| SCHEMBL13372624 | 0.81 | PGR (0.58) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL13372623 | 0.81 | PGR (0.58) | ARPGRNR3C2NR3C1LMNA | |
| SCHEMBL13372649 | 0.79 | AR (0.60) | ARPGRNR3C2LMNACYP3A4 | |
| SCHEMBL13372598 | 0.79 | AR (0.60) | ARPGRNR3C2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | claimed |
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |